주요성과

• 논문목록
  • 2025년
  • 2024년
  • 2023년
  • 2022년
  • 2021년
  • 2020년
  • 2019년

  해당 관련 논문목록과 초록보기 링크 제공

  Addressing overfitting bias due to sample overlap in polygenic risk scoring Alzheimer's & dementia 2025 Apr;21(4):e70109	초록보기
  Development of an MHC imputation panel highlights independent contributions of HLA amino acid residues and C4 copy number variaitions to SLE risk Annals of the Rheumatic Diseases 2025 Dec;84(12):2008-2020	초록보기
  SLC30A8 Rare variants modify contribution of common genetic and lifestyle factors toward type 2 diabetes Diabetes & Metabolism Journal 2025 Jul	초록보기

  해당 관련 논문목록과 초록보기 링크 제공

  Large-scale cross-ancestry genome-wide meta-analysis of serum urate Nature Communications 2024 Apr, 15(1):3441	초록보기
  Inferring compound heterozygosity from large-scale exome sequencing data Nature Genetics 2024 Jan, 56(1):152-161	초록보기
  Genetic drivers of heterogeneity in type 2 diabetes pathophysiology Nature 2024 Mar, 627(8003):347-357	초록보기
  Evaluating cardiovascular disease risk stratification using multiple-polygenic risk score and pooled equation: insights from an 17-year longitudinal Korean cohort study Frontiers in genetics 2024 Mar, 15:1364993	초록보기
  A genomic mutational constraint map using variation in 76,156 human genomes Nature 2024 Mar, 15:1364993	초록보기
  Epigenetic Link between Agent Orange Exposure and Type 2 Diabetes in Korean Veterans Frontiers in Endocrinology 2024 Jul, 15:1375459	초록보기

  해당 관련 논문목록과 초록보기 링크 제공

  Human gain-function variants in HNF1A confer protection from diabetes but independently increase hepatic secretion of atherogenic lipoproteins Cell Genomics 2023;3:100339

  초록보기

  해당 관련 논문목록과 초록보기 링크 제공

  Rare coding variants in 35 genes associate with circulating lipid levels - a multi-ancestry analysis of 170,000 exomes AMERICAN JOURNAL OF HUMAN GENETICS 2022 Jan,109(1):81-96	초록보기
  Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation NATURE GENETICS 2022 May,54(5):560-572	초록보기
  Shared genetic architectures of subjective well-being in East Asian and European ancestry populations Nature Human Behaviour 2022 May,6(7):1014-1026	초록보기
  A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids AMERICAN JOURNAL OF HUMAN GENETICS 2022 Aug,109(8):1366-1387	초록보기
  Phenome-wide association study of the major histocompatibility complex region in the Korean population identifies novel association signals HUMAN MOLECULAR GENETICS 2022 Aug,30(8):716-726	초록보기
  The contribution of common and rare genetic variants to variation in metabolic traits in 288,137 East Asians Nature Communications 2022 Nov,13(1):6642	초록보기
  Analyzing the Korean Reference Genome with meta-imputation increased the imputation accuracy and spectrum of rare variants in the Korean population Frontiers in Genetics 2022 Nov,13:1008646	초록보기

  해당 관련 논문목록과 초록보기 링크 제공

  Genome-Wide Association Studies Identify Two Novel Loci Conferring Susceptibility to Diabetic Retinopathy in Japanese Patients with Type 2 Diabetes HUMAN MOLECULAR GENETICS 2021 May,30(8):716-726	초록보기
  Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes Nature Communications 2021 Jun,12(1):3505	초록보기
  The Trans-Ancestral Genomic Architecture of Glycemic Traits NATURE GENETICS 2021 Jun,53(6):840-860	초록보기
  Genetic variants shape rheumatoid arthritis-specific transcriptomic features in CD4+ T cells through differential DNA methylation, explaining a substantial proportion of heritability ANNALS OF THE RHEUMATIC DISEASES 2021 Jul,80(7):876-883	초록보기
  Unraveling the Genomic Architecture of the CYP3A Locus and ADME Genes for Personalized Tacrolimus Dosing TRANSPLANTATION 2021 Oct,105(10):2213-2225	초록보기
  Expanding the clinical phenotype and genetic spectrum of PURA-related neurodevelopmental disorders BRAIN AND DEVELOPMENT 2021 Oct,43(9):912-918	초록보기
  Validation and genetic heritability estimation of known T2D related variants in the Korean population Genomics & Informatics 2021 Dec,19(4):e37	초록보기

  해당 관련 논문목록과 초록보기 링크 제공

  Identification of type 2 diabetes loci in 433,540 East Asian indiciduals NATURE 2020 May,582(7811):240-245	초록보기
  Integrated Analysis of Tissue-Specific Promoter Methylation and Gene Expression Profile in Complex Diseases International Journal of Molecular Sciences 2020 July,21(14):5056	초록보기
  Obesity susceptible novel DNA methylation marker on regulatory region of inflammation gene: Results from the Korea Epigenome Study (KES) BMJ Open Diabetes Research and Care 2020 Aug,8(1):e001338	초록보기
  GEN2VCF: A converter for human genome imputation output format to VCF format Genes & Genomics 2020 Oct,42(10):1163-1168	초록보기
  Metabolomics profiles associated with diabetic retinopathy in type 2 diabetes patients PLoS One 2020 Oct,15(10):e0241365	초록보기
  Putative positive role of inflammatory genes in fat deposition supported by altered gene expression in purified human adipocytes and preadipocytes from lean and obese adipose tissues Journal of Translational Medicine 2020 Nov,18:433	초록보기
  Identification of metabolic markers predictive of prediabetes in a Korean population Scientific Reports 2020 Dec,10:22009	초록보기

  해당 관련 논문목록과 초록보기 링크 제공

  The Korea Biobank Array: Design and Identification of coding variants associated with blood biochemical Traits Scientific Reports 2019 Feb,9:1382	초록보기
  The genetic and epigenetic association of LDL Receptor Related Protein 1B (LRP1B) gene with obesity related traits from childhood obesity Scientific Reports 2019 Feb,9:1815	초록보기
  Epigenetic analysis in rheumatoid arthritis synoviocytes EXPERIMENTAL AND MOLECULAR MEDICINE 2019 Feb,51(2):22	초록보기
  The association of genetically controlled CpG methylation(cg158269425) of protein tyrosine phosphatase, receptor type N2 (PTPRN2) with childhood obesity Scientific Reports 2019 Mar,9:4855:	초록보기
  Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls NATURE 2019 Jun,570(7759):71-76	초록보기
  Exome chip-driven association study of lipidemia in >14,000 Koreans and evaluation of genetic effect on identified variants between different ethnic groups GENETIC EPIDEMIOLOGY 2019 Sep,43(6):617-628	초록보기
  Programmable nuclease-based integration into novel extragenic genomic safe harbor identified from Korean population-based CNV analysis Molecular Therapy-Oncolytics 2019 Sep,14:253-265	초록보기
  Identification of novel non-synonymous variants associated with type 2 diabetes-related metabolites in Korean population BIOSCIENCE REPORTS 2019 Oct,39(10):BSR20190078	초록보기
  Metabolomics profiles associated with HbA1c levels in patients with type 2 diabetes PLoS One 2019 Nov,:e0224274	초록보기
  Recapitulation of previously reported associations for type 2 diabetes and metabolic traits in the 126K East Asians Genomics & Informatics 2019 Dec,17(4):e48	초록보기