Korea Biobank Network
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Wonkwang University School of Medicine and Hospital (WUSMH)
WUSMH follows the Won Buddhist principle of treating the sickness of the world (je-saeng-eui-se, 濟生醫世) and practices the true values of respect for life. The hospital recruits outstanding medical staff and utilizes cutting-edge equipment to provide local residents with high-quality medical service. As a public medical institution pioneering a healthy society in the 21st century, WUSMH endeavors to createa reliable, patient-centric hospital.
The WUSMH Biobank aims to collect and store human bioresources relating to various diseases and to distribute high-quality human bioresources to researchers in related fields. To address problems relating to the instability of RNA in long-term storage, the Biobank has introduced an RNA dry storage technique and uses RNA extracted from tissue to manufacture and store cDNA. This method is expected to be widely adopted and frequently used by researchers in the future.
Through continuous technological development, and based on knowledge acquired from developing and reporting a new in-house B cell line manufacturing method, the Biobank is beginning to concentrate on the manufacture of various primary cell lines. Through these efforts, the WUSMH Biobank is constantly working to fulfill its role in reinforcing the foundation of innovative medical research.
- February 2002: Establishment of the WUSMH Gene Bank
- October 2004: First distribution of genomic DNA and cell line
- June 2006: Official approval as a gene bank (No. 19) by the Ministry of Health and Welfare
- March 2009: Selection as a Regional Biobank
- December 2009: Opening ceremony for the WUSMH Biobank
- April 2010: Designation as an institution for donation, registration, and preservation (No. 12) by the Ministry of Health and Welfare
- January 2013: : Implementation of Phase 2 of the KBP
Status of Human Bioresources
The main diseases for collection are digestive, respiratory, musculoskeletal, and immune system diseases, as well as neoplastic diseases. The Biobank currently stores human bioresources from approximately 7,500 individuals. These samples include clinical and epidemiological data. The main human biospecimens manufactured and stored are DNA, RNA, cDNA, bone marrow, plasma, serum, and primary cell lines. Since 2014, fat and muscle tissue have been used to manufacture primary cells that can be converted into biospecimens.
Projects and Distribution Results
A total of 39 studies have received distributed human bioresources from the WUSMH Biobank, including studies related to various genetic mutations that affect disease sensitivity. These works have contributed to the publication of 18 research articles in international journals.
Public Relations and Future Plans
Publicity has been conducted through the in-house manufacture and display of posters at the Korean Society for Molecular and Cellular Biology, Korean Society for Biochemistry and Molecular Biology, Korea Genome Organization, and Ribonucleic Acid Society. When training professors in the medical (medicine, dentistry, Oriental medicine, pharmacology) and natural sciences, WUSMH Biobank promotes information concerning distribution and the role of biobanks.
In the future, WUSMH Biobank aims to contribute to the advancement of the domestic medical industry by constructing a more systematic resource collection and storage system, which will be linked with the KBN distribution system, and providing human bioresources to studies attempting to implement the early diagnosis, prevention, and personalized treatment of relevant diseases.
Wonkwang University School of Medicine and Hospital Biobank, 895 Muwang-ro (344-2 Shinyong-dong), Iksan-si, Jeollabuk-do, Korea (54538)
- Tel: 063-859-1816
- Fax: 063-852-2110
- E-mail: firstname.lastname@example.org