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The Korea Acute Myocardial Infarction Registry (KAMIR)-National Institutes of Health (NIH) Registry
Cardiovascular disease is one of the four leading causes of death in Korea. Among cardiovascular diseases, acute myocardial infarction (AMI) is the primary cause of death in the USA, and shows a continuously increasing prevalence in Korea. The prognosis of patients with AMI can be improved by appropriate treatment, and by disease management. For this purpose, many Western countries have established AMI registries, in contrast to Korea, which lacks a nationwide AMI research resource. Therefore, a long-term prospective, government-oriented, nationwide cohort study for AMI is necessary. The aim of the present study is to develop a prospective observational study model to establish an AMI prognosis and surveillance index, for the purpose of AMI prevention and management. The present study will carry out the following: (1) analysis of the current status of the prospective AMI registry in Korea and other countries, (2) development of the prospective observational study model based on the analysis of risk factors, economic burdens, major complications, and prognostic factors in patients, (3) development of AMI management plans, and (4) application of the resulting data to public health policy. Based on the above aims, the present study has set up a nationwide AMI registry network, and will outline the working model for the prospective observational study to establish an AMI prognosis and surveillance index.
Studies show that from November 2011 to October 2015, 13,623 patients were formally diagnosed with AMI. The mean age was 64.1±12.7 years and 73.5% were male. Less than half of the patients (48.2%) were diagnosed with ST-segment elevation AMI (STEMI) (Figure 12). Among the risk factors for ischemic heart disease, hypertension was the most common comorbidity (51.2%), followed by smoking (38.5%), diabetes mellitus (28.6%), dyslipidemia (11.2%), previous MI (8.1%), family history (6.3%), and cerebrovascular accident (6.2%). Although most of the patients with STsegment elevation AMI (90.8%) complained of chest pain, percutaneous coronary intervention was performed in 87.4% of cases and its success rate was very high (99.4%). In-hospital, 1-year mortality was 3.9% and the rate of major adverse cardiac events at 1-year was 9.6%.
Results from the present study will be used as baseline data to develop strategies and policies for the prevention and management of AMI. These results will also provide baseline data and act as a model for future AMI studies.