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Biosafety

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The management of containment laboratories

As biotechnology has improved recently, known and novel pathogens are emerging and reemerging more frequently. As a result, the biosafety practices in bio-medical facilities have become more important. In order to maintain the biosafety capacity of containment facilities in Korea, the national approval and management system for these facilities, such as Biosafety Level 3 (BL3) and Biosafety Level (BL4) facilities, has been developed based on the “Act on Transboundary Movements etc. of LMOs”. After the enactment of Act in 2008, to respond to national bio accident in health sector KCDC set up BL3 facility at first and since then Health Environment Institute and Livestock Experimental Hygiene Station has built and has operated BL3 facilities. Over the past 3 years(2014~2016) in universities(5 units), medical centers(3 units), health service(1 unit), livestock area(6 units), national research institutes(3 units), defense area(2 units) and environment area(1 unit) BL3 facilities are newly set up. Now in December 31, 2016 total 60 units of BL3 facilities are being operated.

Figure 2. The number of approved BL3 facilities.
Over the past 3 years(2014~2016) in universities(5 units), medical centers(3 units), health service(1 unit), livestock area(6 units), national research institutes(3 units), defense area(2 units) and environment area(1 unit) BL3 facilities are newly set up. Now in December 31, 2016 total 60 units of BL3 facilities are being operated. Based upon the recent version of the “Act on Transboundary Movements etc. of LMOs”, we revised the biocontainment facility construction and operation guidelines etc. (ABL3 and BL1, 2 lab.), which includes laboratory accreditation, remodeling, and shutdown procedures. These guidelines are expected to provide lab managers with valuable tools to acquire essential information on design features for biocontainment facilities, the test methodology for validation, and operation procedures.
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