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Pathogen Resource Management: NCCP

Research fields

  • Operation of National Culture Collection for pathogens(NCCP)
  • Research of collecting and preserving and development for pathogens resource
  • Research on bioinformatic analysis of pathogen resources

Research contents

Operation of National Culture Collection for pathogens(NCCP)

  • Collection and deposition of pathogen resource included bacteria, fungi, virus and derivative material
  • Developement of pathogen resource though quality confirmation and analysis of biological properties
  • Preservantion, management and destribution of pathogen resources
  • Management of Pathogens resource network and Promoting international resource exchange

Research of collecting and preserving and development for pathogens resource

  • Development of novel pathogen resources through characteristic analysis of clinical isolates in Korea
  • Development of domestic resource as an alternative strains of National certification test
  • Advancement of identification and analysis technology for pathogen resources using MALDI-TOF MS

Research on bioinformatic analysis of pathogen resources

  • Securement of Next Generation Information Analysis Technology and Infrastructure based on Bigdata of Pathogen Omics
  • Research of Production and Securing of Pathogen resources Information

Major research achievement

Operation of National Culture Collection for pathogens(NCCP)

  • "The Act on the Promotion of Collection, Management, and Utilization of Pathogen Resources (Act No. 13992)" was enacted 2016.·
  • Management of Pathogen resource-network and Cooperation of pathogen resources: signed an MOU for resources exchange and cooperation with DSMZ, Germany in 2011 and 45 strain exchange of resources in 2011 and 2016.

Research for development of pathogen resources

    ·    The NCCP has developed several reference sets for national examination of a domestic trend.
  • Reference set for medical education: Reference set for medical education comprises bacteria, fungi, and viruses (37species, 41strains)
  • Reference set to educate laboratory personnel at public health centers education:
  • Reference set to educate testers at public health centers comprises solely of bacteria (14 species, 22 strains)

Clinically isolated pathogen resources

  • ESBL producing E. coli panel; 1 species 14 strains
  • Food poisioning E. coli panel; 1 species 40 strains
  • pathogenic bacillus panel;      6 species 30strains

Publication

  • Dermabacter jinjuensis sp. nov., a novel species of the 1 genus Dermabacter isolated clinical specimen. International Journal of Systematic and Evolutionary. 2016. Microbiology. 66:2573-2577
  • Resource Development and Investigation of Novel Species from Unidentified Pathogens in NCCP using MALDI-TOF. 2016. Journal of Bacteriology and Virology. 46(4):1-13
  • Taxonomic Identification of Bacillus Species Using Matrix-Assisted Laser esorption/Ionization-Time of Flight Mass Spectrometry. 2016. Ann Clin Microbiol. 19(4):110-120

Analysis of bioinformation for pathogens resources

  • Development of bioinformatic platforms: three new bioinformatic systems such as next generation sequencing analysis disease outbreak investigation, and virulence factor discovery.
  • Genomic and bioinformatics analyses of pathogens: microbial pathogens (MERS-COV, HRSV, HCV, SFTS, ZIKA virus,
  • Influenzae, vibrio cholerae, listeria monocytogenes, Campylobacter jejuni, Shigella sp.)
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