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The predictors for the non-compliance to follow-up among very low birth weight infants in the Korean neonatal network.2018-Paper-041
  • 작성일2019-05-09
  • 최종수정일2019-05-09
  • 담당부서연구기획과
  • 연락처043-719-8033
  • 533
PLOS One, 2018, 13(10), e0204421─0, DOI: https://doi.org/10.1371/journal.pone.0204421

The predictors for the non-compliance to follow-up among very low birth weight infants in the Korean neonatal network.2018-Paper-041

Nam Hyo Kim, Young Ah Youn; Su Jin Cho; Jong-Hee Hwang; Ee-Kyung Kim; Ellen; Ai-Rhan Kim; Soon Min Lee; Korean Neonatal Network

Abstract

    The critical need to emphasize preterm infant follow-up after neonatal intensive care unit (NICU) discharge assures early identification of and intervention for neurodevelopmental disability. The aims of this study were to observe the follow-up rates in high-risk follow-up clinics, and analyze factors associated with non-compliance to follow-up among very low birth weight (VLBW) infants. The data was prospectively collected for 3063 VLBW infants between January 2013 and December 2014 from 57 Korean neonatal network (KNN) centers at a corrected age of 18±24 months. Correlations among demographic data, clinical variables, and neonatal intensive care unit (NICU) volume (divided into 4 quartiles) with the occurrence of non-compliance were analyzed. The overall follow-up rate at the corrected age of 18±24 month was 65.4%. The follow-up rates were inversely related to birth weight and gestational age. Apgar score, hospital stay, maternal age, and maternal education were significantly different between the compliance and non-compliance groups. The follow-up rate was higher for mothers with chorioamnionitis, abnormal amniotic fluid, multiple pregnancy, and in vitro fertilization. Infants with respiratory distress syndrome, bronchopulmonary dysplasia, patent ductus arteriosus ligation, periventricular leukomalacia, and retinopathy of prematurity were more common in the compliance group. Follow-up rates showed significant differences according to NICU volume. Using multivariate logistic regression, high birth weight, low NICU volume, siblings, foreign maternal nationality and high 5 min APGAR scores were significant independent factors associated with the non-compliance of VLBW infants for follow-up at 18±24 months of age. This is the first nation-wide analysis of follow-up for VLBW infants in Korea. Understanding factors associated with failure of compliance could help improve the long-term follow-up rates and neurodevelopmental outcomes through early intervention.



  • 본 연구는 질병관리본부 연구개발과제(과제번호 2016-ER6307-02) 연구비를 지원받아 수행되었습니다.
  • This research was supported by a fund(code 2016-ER6307-02) by Research of Korea Centers for Disease Control and Prevention.


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